Stephen Schumacher
- Secretary of State: Marco Rubio
- Secretary of the Treasury: Scott Bessent
- Secretary of Defense: Pete Hegseth
- Attorney General: Pam Bondi
- Secretary of the Interior: Doug Burgum
- Secretary of Agriculture: Brooke Rollins
- Secretary of Commerce: Howard Lutnick
- Secretary of Labor: Lori Chavez-DeRemer
- Secretary of Health and Human Services: Robert F. Kennedy Jr.
- Secretary of Housing and Urban Development: Scott Turner
- Secretary of Transportation: Sean Duffy
- Secretary of Energy: Chris Wright
- Secretary of Education: Linda McMahon
- Secretary of Veterans Affairs: Doug Collins
- Secretary of Homeland Security: Kristi Noem
Ambassadorial Appointments:
- United Nations: Elise Stefanik
- Israel: Mike Huckabee
- France: Charles Kushner
- United Kingdom: Warren Stephens
- Japan: George Glass
- China: David Perdue
- Greece: Kimberly Guilfoyle
- Turkey: Tom Barrack
- Canada: Pete Hoekstra
- Ireland: Edward S. Walsh
- Luxembourg: Stacey Feinberg
- Portugal: John Arrigo
- Panama: Kevin Marino Cabrera
- Argentina: Peter Lamelas
- Colombia: Dan Newlin
- Chile: Brandon Judd
- Dominican Republic: Leah Campos
- Austria: Arthur Fisher
- Bahamas: Herschel Walker
- Italy: Tilman Fertitta
- Mexico: Ronald D. Johnson
- Holy See (Vatican City): Brian Burch
- Belgium: Bill White
Special Envoys and Other Appointments:
- National Security Advisor: Michael Waltz
- Presidential Envoy for Special Missions: Richard Grenell
- Special Envoy for Latin America: Mauricio Claver-Carone
- Special Envoy to the United Kingdom: Mark Burnett
- Special Envoy for the Middle East: Steven Witkoff
- Special Envoy for Ukraine and Russia: Keith Kellogg
- Border Czar: Thomas Homan